By Alvin H. Sacks Ph.D. (auth.), Daniel J. Schneck (eds.)

The division of Engineering technology and Hechanics at Virginia Polytechnic Institute and nation college spon sored the 1st Mid-Atlantic convention on Bio-Fluid Mechanics, which used to be held in Blacksburg, Virginia throughout the interval 9/11 August 1978. a few forty life-scientists, engineers, physicians and others who proportion a standard curiosity within the development of easy and utilized wisdom in bio fluid mechanics amassed on the Donaldson Brown middle for carrying on with schooling to listen to 25 papers awarded in seven technical classes. on the end of the convention, these current determined unanimously that its luck warranted having at the very least yet another -- and that it used to be conceptually a legitimate inspiration to devise it on a biennial foundation for past due spring. consequently, the second one Mid-Atlantic convention on Bio Fluid Mechanics came about at Virginia Tech on may perhaps 4-6, 1980. This quantity records the complaints of the second one convention. It comprises complete texts of 23 contributed papers, 2 visitor lectures and 1 invited seminar. The papers are gr9uped based on subject material, starting with three within the zone of respiratory, via 1 in kidney dialysis, 1 in replica, 1 in joint lubrication, 1 in prosthetic fluidics, 2 in zoology, and finishing with 14 within the normal box of cardiovascular dynamics. Of the latter, five care for the topic of center valves, 2 predicament themselves with the microcirculation, 6 deal with vascular procedure hemodynamics and 1 covers a few elements of blood rheology.

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THE PRESSURE-FLOW RELATION IN BRONCHIAL AIRWAYS 55 9. Narks, L. echanical Engineers Handbook. McGrawHill Book Company, 5th Edition, p. 1624, New York, 1951. 10. Prandtl, L. and Tietjens, 0. : Applied Hydro- and Aeromechanics. Dover Publ. Chap. 3, New York, 1934. 11. Heibel, E. : Morphometry of the Human Lung. , Chap. 11, New York, 1963. 12. Hyatt, R. E. and Wilcox, R. : The Pressure-Flow Relationships of the Intrathoracic Airway in lfun. Jour. Clin. Investigation, Vol. 42. No. 1, pp. 29-39, 1963.

SeC) b) FAST EXHALATION (maximal) Ref. 931 Female, Age 38 w 0 z i=! 6 . 23 MEAN UNIDIRECTIONAL FLOW (t/sec) I II III IV V VI VII Vlll IX X TENTH VOLUME RANGES EXHALED Figure 5. 009 1. 862 rejected t{(Resista nce to Unidirecti onal Flow) - (Resistanc e to Sinusoidal Flow)} . . max1ma 1 ex h a 1 a t"1on -{correspo nd1ng D1fference } 1 h 1 . s ow ex a at1on All SlRlE5 vs SlRlE4 1 S3R3E5,S3R5~5 SlRlE3 vs SlRlE2 Expiration s Compared 1 Subject No. ) '-J :E r 0 -n )> Cll G> -< :0 -t 0 :0 )> "tJ X m -n 0 s: Cll z c;; )> ::c (") s: m c=; s: )> z-< 0 WILLIS G.

Va 1 ue to res~stance . ,v L"- Table 1 makes the lung resistance comparisons described above for 6 pairs of single exhalations (2 pairs per subject) statistically. " The matched-pair (or correlated) t-test was used to analyze the significance of this difference. To make this comparison, the mean of the differences of the differences is first calculated. That is, the resistance to VL"- is first subtracted from the resistance to V for a maximal exhalation of a subject at the same corre~~onding tenth volume ranges.